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The respiratory depressant effects of opioids include carbon dioxide retention and secondary elevation of cerebrospinal fluid strain, and may be markedly exaggerated during the existence of head injuries, other intracranial lesions or possibly a pre-current boost in intracranial strain.to people in circulatory shock, because vasodilation made by th

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The risk of acute liver failure is higher in men and women with underlying liver disorder As well as in people who ingest Alcoholic beverages when using acetaminophen.Actual physical dependence happens when One's body develops a tolerance towards the drug, requiring extra of it to achieve a certain impact.Abuse and habit are different and distincti

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